BBS

Wissenschaftliche Publikationen

Originalbeiträge in Fachzeitschriften

Cavedo E, Suppa P, Lange C, Opfer R, Lista L, Galluzzi S, Schwarz AJ, Spies L, Buchert R, Hampel H (2017) Fully automatic MRI-based hippocampus volumetry using FSL-FIRST: intra-scanner test-retest stability, inter-field strength variability, and performance as enrichment biomarker for clinical trials using prodromal target populations at risk for Alzheimer's disease. J Alzheimers Dis; DOI 10.3233/JAD-161108
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Schippling S, Ostwaldt AC, Suppa P, Spies L, Manogaran P, Gocke C, Huppertz HJ und Opfer R (2017) Global and regional annual brain volume loss rates in physiological aging. J Neurol 264:520-528.
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Egger C, Opfer R, Wang C, Kepp T, Sormani MP, Spies L, Barnett M, and Schippling S (2017) MRI FLAIR lesion segmentation in Multiple Sclerosis: Does automated segmentation hold up with manual annotation? NeuroImage: Clinical 13:264–270.
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Lange C, Suppa P, Mäurer A, Ritter K, Pietrzyk U, Steinhagen-Thiessen E, Fiebach JB, Spies L, and Buchert R (2016) Mental speed is associated with the shape irregularity of white matter MRI hyperintensity load. Brain Imaging and Behavior; DOI 10.1007/s11682-016-9647-x
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Ritter K, Lange C, Weygandt M, Mäurer A, Roberts A, Estrella M, Suppa P, Spies L, Prasad V, Steffen I, Apostolova I, Bittner D, Gövercin M, Brenner W, Mende C, Peters O, Seybold J, Fiebach JB, Steinhagen-Thiessen E, Hampel H, Haynes JD, and Buchert R (2016) Combination of structural MRI and FDG-PET of the brain improves diagnostic accuracy in newly manifested cognitive impairment in geriatric inpatients. J Alzheimers Dis 54:1319–1331.
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Suppa P, Hampel H, Kepp T, Lange C, Spies L, Fiebach JB, Dubois B, Buchert R (2016) Performance of hippocampus volumetry with FSL-FIRST for prediction of Alzheimer's disease dementia in at risk subjects with amnestic mild cognitive impairment. J Alzheimers Dis 51:867-873.
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Opfer R, Suppa P, Kepp T, Spies L, Schippling S und Huppertz HJ (2016) Atlas based brain volumetry: how to distinguish regional volume changes due to biological or physiological effects from inherent noise of the methodology. Magn Reson Imaging 34:45-461.
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Lange C, Suppa P, Frings L, Brenner W, Spies L und Buchert R (2016) Optimization of Statistical Single Subject analysis of Brain FDG PET for the Prognosis of Mild Cognitive Impairment-to-Alzheimer’s Disease Conversion. J Alzheimers Dis 49:945-959.
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Burkhardt T, Lüdecke D, Spies L, Wittmann W, Westphal M und Flitsch J (2015) Hippocampal and cerebellar atrophy in patients with Cushing’s disease. Neurosurg Focus 39:E5
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Suppa P, Hampel H, Spies L, Fiebach J, Dubois B und Buchert R (2015) Fully automated atlas-based hippocampal volumetry for clinical routine: validation in subjects with mild cognitive impairment from the ADNI cohort. J Alzheimers Dis 46:199–209.
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Suppa P, Anker U, Spies L, Bopp I, Rüegger-Frey B, Klaghofer R, Gocke C, Hampel H, Beck S und Buchert R (2015) Fully automated atlas-based hippocampal volumetry for detection of Alzheimer’s disease in a memory clinic setting. J Alzheimers Dis 44:183–193.
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Boelmans K, Spies L, Sedlacik J, Fiehler J, Jahn H, Gerloff C, Münchau A. (2014) A novel computerized algorithm to detect microstructural brainstem pathology in Parkinson's disease using standard 3 Tesla MR imaging. J Neurol 261:1968-75
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Spies L, Tewes A, Suppa P, Buchert R, Winkler G und Raji A. (2013) Fully automatic detection of deep white matter T1 hypointense lesions in multiple sclerosis. Phys Med Biol 58:8323–37.
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Arlt S, Buchert R, Spies L, Eichenlaub M, Lehmbeck J und Jahn H. (2013) Association between fully automated MRI based volumetry of different brain regions and neuropsychological test performance in patients with mild cognitive impairment and early dementia. Eur Arch Psychiatry Clin Neurosci 263:335-44.
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Ausgewählte Konferenzbeiträge

Peters O, Suppa P, Haas B, Buchert R, Spies L, Heuser I (2016) Robustness of MRI-based volumetry for the prediction of short-term conversion from mild cognitive impairment to Alzheimer´s dementia. CTAD, San Diego, USA
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Opfer R, Suppa P, Spies L, Egger C, Schippling S (2016) Consistency of longitudinal brain volume loss assessment in MS using SIENA/FSL. ECTRIMS, London, UK
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Opfer R, Kepp T, Suppa P, Spies L, Egger C, Schippling S (2015) Assessing intra- and interscanner variability of automated brain volumetry using SPM12, SIENA, SIENAX. ECTRIMS, Barcelona, Spain
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